1 Product identity
Ingredient risk
2 ingredients to use with caution

Herbal Actives Cascara Sagrada 100 mg/25-30% Hydroxyanthracene Derivatives

BrandNature's PlusBotanical Capsule 6 ingredients 2 caution DSLD #49349
Net contents: 60 Vegetarian Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2015-08-25
2 Ingredients (6)
IngredientGroupSafety
Cascara SagradaCascara SagradaUse with Caution
Microcrystalline CelluloseCellulose
Vegetable CelluloseCellulose
SilicaSiliconGenerally Safe
Magnesium StearateMagnesiumUse with Caution
purified WaterWater
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Cascara Sagrada  🇪🇺 — Hydroxyanthracene derivatives under assessment.
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Cascara Sagrada — Use with Caution
⚠ Stimulant laxative — same chronic abuse risk as senna
⚠ Electrolyte imbalance
Silicon — Generally Safe
⚠ Very low toxicity
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID49349
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2015-08-25
6 More from Nature's Plus
View Nature's Plus Safety Scorecard → 26 products
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7 Cite this page
Vancouver
Pkhakadze G. Herbal Actives Cascara Sagrada 100 mg/25-30% Hydroxyanthracene Derivatives — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 26]. Available from: https://supplement.ge/products/herbal-actives-cascara-sagrada-100-mg-25-30-hydroxyanthracene-derivatives-49349/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG