1 Product identity
Ingredient risk
2 ingredients to use with caution
Herbal Actives Cascara Sagrada 100 mg/25-30% Hydroxyanthracene Derivatives
BrandNature's Plus→Botanical Capsule 6 ingredients 2 caution DSLD #49349Net contents: 60 Vegetarian Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2015-08-25
2 Ingredients (6)
IngredientGroupSafety
Microcrystalline CelluloseCellulose—
Vegetable CelluloseCellulose—
purified WaterWater—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Cascara Sagrada 🇪🇺 — Hydroxyanthracene derivatives under assessment.
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Cascara Sagrada — Use with Caution
⚠ Stimulant laxative — same chronic abuse risk as senna
⚠ Electrolyte imbalance
Silicon — Generally Safe
⚠ Very low toxicity
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID49349
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2015-08-25
6 More from Nature's Plus
View Nature's Plus Safety Scorecard → 26 products
Advanced Therapeutics Glucofit Rx-Blood SugarAdvanced Therapeutics Huperzine Rx-BrainAdvanced Therapeutics Ribose Rx-EnergyAlfalfa 8 1/2 GrainAntioxidant Formula Ultra ActivinApple Pectin 500 mg7 Cite this page
Vancouver
Pkhakadze G. Herbal Actives Cascara Sagrada 100 mg/25-30% Hydroxyanthracene Derivatives — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 26]. Available from: https://supplement.ge/products/herbal-actives-cascara-sagrada-100-mg-25-30-hydroxyanthracene-derivatives-49349/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG