1 Product identity

Ingredient risk

Contains a high-risk ingredient

Estro-Mend

Name: Estro-Mend
Brand: Douglas Laboratories

BrandDouglas Laboratories→Other Combinations Capsule 19 ingredients 1 high-risk 1 caution DSLD #6658

Net contents: 90 Capsule(s)

Target: Adults and Children 4 years and above

DSLD entry: 2012-03-23

2 Ingredients (19)

IngredientGroupSafety

Isoflavone Complex Herbal Proprietary BlendProprietary Blend (Herb/Botanical)—

Pueraria IobataKudzu —

Red CloverRed CloverConditionally Safe

Novasoy Isoflavone ConcentrateSoy Isoflavones—

Black CohoshBlack CohoshHigh risk

Estromend Herbal Proprietary BlendProprietary Blend—

Bacopa monnieraBacopaConditionally Safe

Cranberrycranberry—

Dong QuaiDong QuaiLimited Evidence

SchisandraSchisandraGenerally Safe

SageSage—

HopsHops —

GelatinGelatin—

Dicalcium PhosphateCalciumConditionally Safe

CelluloseCellulose—

Vegetable StearateMagnesium stearateUse with Caution

SilicaSiliconGenerally Safe

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ High-risk ingredient — documented serious harm

Black Cohosh 🇺🇸 🇦🇺 🇪🇺 — Hepatotoxicity cases including liver failure — limit 6 months [1]

⚠️ Use with caution — restricted in some markets

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

3 Safety cross-reference

Red Clover — Conditionally Safe

⚠ Estrogenic (isoflavones)

⚠ May increase bleeding risk

Black Cohosh — High risk

⚠ HEPATOTOXICITY (rare but serious)

⚠ Limit to 6 months

Bacopa — Conditionally Safe

⚠ GI upset

⚠ May affect thyroid

Dong Quai — Limited Evidence

⚠ Anticoagulant effect (coumarin)

⚠ Photosensitivity

Schisandra — Generally Safe

⚠ GI discomfort

⚠ May affect CYP enzymes

Calcium — Conditionally Safe

⚠ Cardiovascular risk debated >1,000 mg/day

⚠ Kidney stones

Magnesium — Use with Caution

Silicon — Generally Safe

⚠ Very low toxicity

4 Label claims

• All Other

5 Data source

DSLD ID6658

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2012-03-23

6 More from Douglas Laboratories

View Douglas Laboratories Safety Scorecard → 788 products

A-Potene 10 A-Potene 25 A-Retic Natural Herbal Formula A-Retic Natural Herbal Formula A.R. Formula A.R.M.D. Eye Support

7 Cite this page

Vancouver

Pkhakadze G. Estro-Mend — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 25]. Available from: https://supplement.ge/products/estro-mend-6658/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG