1 Product identity

Ingredient risk

Contains a high-risk ingredient

EsophaCool

Name: EsophaCool
Brand: Life Extension

BrandLife Extension→Botanical with Nutrients Tablet or Pill 15 ingredients 1 high-risk 1 caution DSLD #232679

Net contents: 60 Chewable Tablet(s)

Target: Adults and Children 4 years and above

DSLD entry: 2020-08-23

2 Ingredients (15)

IngredientGroupSafety

CalciumCalciumConditionally Safe

MagnesiumMagnesiumUse with Caution

GutGard Deglycyrrhizinated Licorice (DGL) extractLicorice —

XylitolXylitolHigh risk

MannitolMannitol—

FlavorsFlavor—

Microcrystalline CelluloseCellulose—

Stearic AcidStearic Acid—

DextrinDextrin—

Citric AcidCitric Acid—

Croscarmellose SodiumCroscarmellose Sodium—

Gum ArabicAcacia—

SilicaSiliconGenerally Safe

Vegetable StearateMagnesium stearateUse with Caution

Stevia extractStevia—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ High-risk ingredient — documented serious harm

Xylitol — Dog owner not warned about xylitol toxicity — potentially fatal to dogs [1]

⚠️ Use with caution — restricted in some markets

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

3 Safety cross-reference

Calcium — Conditionally Safe

⚠ Cardiovascular risk debated >1,000 mg/day

⚠ Kidney stones

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

Xylitol — High risk

⚠ GI distress (gas, bloating, diarrhea) dose-dependent

⚠ Cardiovascular risk: 2023 Cleveland Clinic study linked xylitol to increased thrombotic events

Sodium — Limited Evidence

⚠ Hypertension

⚠ Fluid retention

Silicon — Generally Safe

⚠ Very low toxicity

4 Label claims

• Nutrient

• All Other

• Structure/Function

5 Data source

DSLD ID232679

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2020-08-23

6 More from Life Extension

View Life Extension Safety Scorecard → 201 products

Acetyl-L-Carnitine Arginate Adrenal Energy Formula Advanced Cortisol Balance Advanced Oral Hygiene AM Anti-Alcohol Complex

7 Cite this page

Vancouver

Pkhakadze G. EsophaCool — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jun 28]. Available from: https://supplement.ge/products/esophacool-232679/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG