1 Product identity
Ingredient risk
Contains a high-risk ingredient
Clinical Dyspepsia
BrandNatural Clinician→Other Combinations Tablet or Pill 17 ingredients 1 high-risk 2 caution DSLD #18621Net contents: 60 Chewable Tablet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2013-02-25
2 Ingredients (17)
IngredientGroupSafety
Holt MD Proprietary BlendProprietary Blend (Combination)—
FructoseFructose—
SorbitolSorbitol—
MannitolMannitol—
Beet JuiceBeet—
RaspberryRaspberry (unspecified)—
Cherry and Vanilla FlavorsFlavor—
SteviaStevia—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Xylitol — Dog owner not warned about xylitol toxicity — potentially fatal to dogs [1]
⚠️ Use with caution — restricted in some markets
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin A — Conditionally Safe
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Sodium — Conditionally Safe
⚠ Hypertension
⚠ Fluid retention
Vitamin E — Limited Evidence
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Xylitol — High risk
⚠ GI distress (gas, bloating, diarrhea) dose-dependent
⚠ Cardiovascular risk: 2023 Cleveland Clinic study linked xylitol to increased thrombotic events
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID18621
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2013-02-25
6 More from Natural Clinician
View Natural Clinician Safety Scorecard → 28 products
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Vancouver
Pkhakadze G. Clinical Dyspepsia — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Oct 18]. Available from: https://supplement.ge/products/dsld-18621/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG