1 Product identity
Ingredient risk
4 ingredients to use with caution
Cramprin +BioPerine
BrandApproved Science→Botanical with Nutrients Tablet or Pill 18 ingredients 4 caution DSLD #319745Net contents: 60 Tablet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2024-10-24
2 Ingredients (18)
IngredientGroupSafety
B-Sci Vitamin B ComplexProprietary Blend—
Vitamin B5Vitamin B5—
Chamomile, PowderChamomile—
Ginger, PowderGinger —
BioPerineBlack Pepper—
Microcrystalline CelluloseCellulose—
Stearic AcidStearic Acid—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Thiamin — Use with Caution
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• Nutrient
• All Other
• Structure/Function
5 Data source
DSLD ID319745
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2024-10-24
6 More from Approved Science
View Approved Science Safety Scorecard → 7 products
CLA MDEvening Primrose OilMagnesium ComplexNauseprinOmega 3-6-9Stressyl +BioPerine7 Cite this page
Vancouver
Pkhakadze G. Cramprin +BioPerine — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jun 24]. Available from: https://supplement.ge/products/cramprin-bioperine-319745/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG