1 Product identity
Ingredient risk
2 ingredients to use with caution

Cascara Sagrada 450 mg

BrandSunshine Naturals→Botanical Capsule 6 ingredients 2 caution DSLD #271167
Net contents: 100 Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2022-07-21
2 Ingredients (6)
IngredientGroupSafety
Cascara SagradaCascara SagradaUse with Caution
WheyWhey—
Dicalcium PhosphateCalciumConditionally Safe
Microcrystalline CelluloseCellulose—
Silicon DioxideSiliconGenerally Safe
Magnesium StearateMagnesium stearateUse with Caution
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Cascara Sagrada  🇪🇺 — Hydroxyanthracene derivatives under assessment.
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Cascara Sagrada — Use with Caution
⚠ Stimulant laxative — same chronic abuse risk as senna
⚠ Electrolyte imbalance
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Silicon — Generally Safe
⚠ Very low toxicity
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID271167
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2022-07-21
6 More from Sunshine Naturals
View Sunshine Naturals Safety Scorecard → 38 products
Alfalfa 500 mgAloe Vera 5000 mg ExtractAmino-Acid Complex 1200 mgAnamu 450 mgAntioxidantCanadian Golden Flaxseed
7 Cite this page
Vancouver
Pkhakadze G. Cascara Sagrada 450 mg — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 26]. Available from: https://supplement.ge/products/cascara-sagrada-450-mg-271167/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG