1 Product identity

Ingredient risk

Contains a high-risk ingredient

Estrotone

Name: Estrotone
Brand: New Chapter

BrandNew Chapter→Botanical Softgel Capsule 20 ingredients 1 high-risk DSLD #38805

Net contents: 120 Softgel(s)

Target: Adults and Children 4 years and above

DSLD entry: 2014-10-27

2 Ingredients (20)

IngredientGroupSafety

Evening Primrose Oil (Oenothera biennis) (seed) supercritical extractEvening Primrose oilConditionally Safe

Schizandra (Schisandra chinensis) (berry) extractSchisandraGenerally Safe

min. 3.2 mg SchizandrinsSchisandrin—

min. 6 mg pungent compoundsPungent compounds (unspecified)—

Ginger essential OilGinger —

min. 0.7 mg pungent compoundsPungent compounds (unspecified)—

GingerGinger —

Ginger supercritical extractGinger —

Ginger hydroethanolic extractGinger —

min. 1 mg Triterpene GlycosideTriterpene (unspecified)—

min. 0.4 mg Iridoidsiridoids—

min. 1.2 mg Total Phenolic AntioxidantsPhenolics (unspecified)—

Black Cohosh (Cimicifuga racemosa) (root and rhizome) extractBlack CohoshHigh risk

Chaste Tree (Vitex agnus-castus) (berry) extractChastetree—

Rosemary (Rosmarinus officinalis) (leaf) supercritical extractRosemary —

Capsulecapsule—

extra-virgin Olive OilOlive Oil—

MaltodextrinMaltodextrin—

yellow BeeswaxBeeswax—

organic Sunflower OilSunflower Oil—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ High-risk ingredient — documented serious harm

Black Cohosh 🇺🇸 🇦🇺 🇪🇺 — Hepatotoxicity cases including liver failure — limit 6 months [1]

3 Safety cross-reference

Evening Primrose oil — Conditionally Safe

⚠ May lower seizure threshold

⚠ Increased bleeding risk

Schisandra — Generally Safe

⚠ GI discomfort

⚠ May affect CYP enzymes

Black Cohosh — High risk

⚠ HEPATOTOXICITY (rare but serious)

⚠ Limit to 6 months

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID38805

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2014-10-27

6 More from New Chapter

View New Chapter Safety Scorecard → 79 products

40+ Every Man II Multivitamin 40+ Every Man II Multivitamin 40+ Every Man's One Daily Multi 40+ Every Woman II Multivitamin 40+ Every Woman's One Daily Multi Activated C Food Complex

7 Cite this page

Vancouver

Pkhakadze G. Estrotone — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Oct 19]. Available from: https://supplement.ge/products/estrotone-38805/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG