Active warning — SupplementIndex Safety Review: FDA/FTC action. Fraudulent.
Updated: 2026-05-29 · v2.0 · Prof. G. Pkhakadze, MD, MPH, PhDCiteEditorial
📰Read the full HCG Diet Drops/Pellets evidence review on GMJ News →Complete clinical article, references and updates on news.gmj.ge. This page is the structured safety summary.
5
Avoid
HCG Diet Drops/Pellets
Human chorionic gonadotropin (OTC forms)
Use with CautionStrongRestricted
RDA
NOT effective for weight loss
Target
N/A
Upper limit
No safe OTC dose for weight loss
Products
Dosage by population group — reference
⚠ HIGH RISK — see overview [1]
ℹ️ Not obtained from food. Not applicable — this substance is not a dietary nutrient and should not be consumed as food.
🔬 Lab interpreter
ℹ️ No validated blood test. There is no established laboratory test to assess status or guide dosing for this ingredient. Clinical response and symptoms are the practical guide.
⚕ For professionals — confirm ranges against your local laboratory.
Clinical verdict
HCG diet is DOUBLE fraud: (1) HCG provides NO weight loss benefit beyond starvation (meta-analysis); (2) most OTC 'HCG drops' contain NO detectable HCG (homeopathic dilution = water). FDA declared OTC HCG weight-loss products ILLEGAL. The 500 kcal/day diet causes muscle wasting, gallstones, electrolyte disturbance, and eating disorder. Any weight loss is from starvation, not HCG. Patients buying these products are paying for a label on a water bottle [1].
1 How much do I need?
👤 Adults: Specific dosage data under clinical review
👴 Elderly: Specific dosage data under clinical review
🤰 Pregnancy: See guidance
IRRELEVANT to pregnancy context — HCG diet is NOT for pregnant women (despite HCG being a pregnancy hormone) [1].
👦 Pediatric: See guidance
Not recommended [1].
🏃 Athletes: Standard dose
⚖️ Obesity: Standard dose
Fat-soluble compounds may require dose adjustment in obesity.
🩺 Renal: Consult specialist
Dose adjustment may be needed in renal impairment.
🌱 Vegan: Standard dose

How to take

🍽 Timing: See overview [1].
💊 With food: See overview [1].
🚫 Avoid: See overview for contraindications [1].
2 Which form?
FormBioavailabilityVeganCost
['Various', 'see overview', 'See overview for forms and risks [1].']StandardCheck label
3 Common questions
Key safety point
HCG diet is DOUBLE fraud: (1) HCG provides NO weight loss benefit beyond starvation (meta-analysis); (2) most OTC 'HCG drops' contain NO detectable HCG (homeopathic dilution = water). FDA declared OTC HCG weight-loss products ILLEGAL. The 500 kcal/day diet causes muscle wasting, gallstones, electrolyte disturbance, and eating disorder. Any weight loss is from starvation, not HCG. Patients buying these products are paying for a label on a water bottle [1].
4 Clinical evidence

Strong

See overview [1]. HIGH

Moderate

See overview [1]. MODERATE

Insufficient

See overview [1]. LOW
5 Safety, toxicity & adverse events

Absolute contraindications

✕ Should not be used for weight loss — OTC and homeopathic 'HCG' drops are prohibited and contain no active hormone
✕ Hormone-sensitive cancers (prostate, breast, ovarian)
✕ Pregnancy

Relative

⚠ The accompanying ~500 kcal diet is itself hazardous — gallstones, arrhythmia, electrolyte loss
⚠ Thromboembolic disorders

🚩 Red flags

HIGH RISK — see overview for critical safety alerts [1]
6 Interactions
7 Cite this page
Vancouver: Pkhakadze G. HCG Diet Drops/Pellets — safety profile [Internet]. Tbilisi: PHIG; 2026 [cited 2026 Jul 12]. Available from: https://supplement.ge/ingredients/hcg-diet-drops-pellets/
APA 7th: Pkhakadze, G. (2026). HCG Diet Drops/Pellets — Safety profile. Public Health Institute of Georgia. https://supplement.ge/ingredients/hcg-diet-drops-pellets/
📋 Editorial information
Author: Prof. G. Pkhakadze, MD, MPH, PhD
Affiliation: David Tvildiani Medical University (DTMU)
First published: January 2026
Last reviewed: 2026-05-29
Next review: January 2027
References: 2 cited sources
COI: SupplementIndex receives no funding from supplement manufacturers. All content independently authored by PHIG.
Process: Systematic literature review
📄 License & reuse
Published under Creative Commons Attribution 4.0 International (CC BY 4.0). You may share and adapt for any purpose with attribution.
Pkhakadze G. "HCG Diet Drops/Pellets — Safety Profile." SupplementIndex, PHIG, 2026. https://supplement.ge/ingredients/hcg-diet-drops-pellets/ CC BY 4.0.
GP
Prof. G. Pkhakadze, MD, MPH, PhD
Professor of Public Health · Head of Department, DTMU
Editor-in-Chief, Georgian Medical Journal (ISSN 3088-4322)
Chair, Public Health Institute of Georgia · UEMS Public Health Section
Educational and public health purposes. CC BY 4.0. Consult your healthcare provider before starting any supplement. Corrections: info@accreditation.ge. Publisher: PHIG