No active regulatory warningsFDA, EMA, WHO
2
Conditional
Devil's Claw
Harpagophytum procumbens
Conditionally SafeModerateBotanicals
RDA
Typical 600–2,400 mg
Target
Upper limit
No UL
Products
ℹ️ Not obtained from food. Not obtained from food in meaningful amounts — supplementation is the practical route.
🔬 Lab interpreter
ℹ️ No validated blood test. There is no established laboratory test to assess status or guide dosing for this ingredient. Clinical response and symptoms are the practical guide.
⚕ For professionals — confirm ranges against your local laboratory.
1 Dosage
📋 Specific dosage data under clinical review. Consult your healthcare provider for personalized guidance.
2 Common questions
What is the recommended dose of Devil's Claw?
The recommended daily allowance is Typical 600–2,400 mg. The upper tolerable intake level is No UL. Individual requirements may vary based on age, health status, and other factors. Consult your healthcare provider for personalized dosing.
Is Devil's Claw safe to take?
Devil's Claw is classified as "Conditionally Safe" in the SupplementIndex database. As with any supplement, consult your healthcare provider before starting, especially if you take medications or have medical conditions.
Who should avoid Devil's Claw?
Documented contraindications include: Gastric/duodenal ulcers, Gallstones, Pregnancy. This list may not be exhaustive. Consult your physician.
3 Safety, toxicity & adverse events
4 Regulatory
General: Classified as dietary supplement in most jurisdictions. Country-specific regulatory data under review.
5 Related articles
📰 Article — news.gmj.ge📰 Article — news.gmj.ge📰 Article — news.gmj.ge📰 Article — news.gmj.ge
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6 Cite this page
Vancouver: Pkhakadze G. Devil's Claw — safety profile [Internet]. Tbilisi: PHIG; 2026 [cited 2026 Jun 01]. Available from: https://supplement.ge/ingredients/devils-claw/
APA 7th: Pkhakadze, G. (2026). Devil's Claw — Safety profile. Public Health Institute of Georgia. https://supplement.ge/ingredients/devils-claw/
📋 Editorial information
Author: Prof. G. Pkhakadze, MD, MPH, PhD
Institution: Public Health Institute of Georgia (PHIG)
Affiliation: David Tvildiani Medical University (DTMU)
First published: January 2026
Last reviewed: 2026-06-01
Next review: December 2026
References: 0 cited sources
COI:
Process: Systematic literature review
📄 License & reuse
Published under Creative Commons Attribution 4.0 International (CC BY 4.0). You may share and adapt for any purpose with attribution.
Pkhakadze G. "Devil's Claw — Safety Profile." SupplementIndex, PHIG, 2026. https://supplement.ge/ingredients/devils-claw/ CC BY 4.0.
GP
Prof. G. Pkhakadze, MD, MPH, PhD
Professor of Public Health · Head of Department, DTMU
Editor-in-Chief, Georgian Medical Journal (ISSN 3088-4322)
Chair, Public Health Institute of Georgia · UEMS Public Health Section
Educational and public health purposes. CC BY 4.0. Consult your healthcare provider before starting any supplement. Corrections: info@accreditation.ge. Publisher: PHIG