RISK

Colloidal silver

Colloidal silver nanoparticles (Ag)
Likely Unsafe V2 Verified Specialty Bioactives
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PubMed Studies
6
PubChem CID
About

Colloidal suspension of silver nanoparticles marketed for antimicrobial, immune-boosting, and anti-aging effects. FDA ruled in 1999 that colloidal silver is NOT generally recognised as safe (GRAS) for any condition. EFSA and TGA concur. Causes argyria (irreversible blue-grey skin discolouration). No legitimate supplement use.

How it works (mechanism of action)

Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralLikely unsafeNot established
PregnancyLikely unsafeNot established
ElderlyLikely unsafeNot established
🚫 Contraindications & Warnings

FDA 1999 FINAL RULE: colloidal silver products are NOT safe or effective for any condition claimed. ARGYRIA: Irreversible permanent blue-grey/slate discolouration of skin, mucous membranes, and organs due to silver accumulation — no treatment exists. Neurological toxicity. Antibiotic interference (reduces absorption of antibiotics). Drug interactions: tetracyclines, quinolone antibiotics, penicillamine, thyroxine. Banned/restricted as supplement in USA, EU, Australia, Canada.

🏷️ Other Names
Colloidal silver nanoparticles (Ag)
Updated: 2026-04-11
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