✓
No active regulatory warnings
Sources: FDA MedWatch, EMA EudraVigilance, WHO VigiBase, WADA Prohibited List · 2026-05-29
Updated: 2026-05-29 · v2.0 · Prof. G. Pkhakadze, MD, MPH, PhD📎 Cite 📄 PDF
1 Identity

Hydrazine Sulfate

Hydrazine sulfate
BannedEvidence: ModerateRestricted
Hydrazine sulfate was promoted by Joseph Gold (1970s) as a cancer 'cachexia cure' based on inhibition of gluconeogenesis via phosphoenolpyruvate carboxykinase [1]. Three NCI-sponsored RCTs found NO benefit and INCREASED TOXICITY (hepatotoxicity, neurotoxicity) vs placebo. Hydrazine is also a ROCKET FUEL component and a KNOWN CARCINOGEN (IARC Group 2B). Despite negative trials and carcinogenicity, hydrazine sulfate is still promoted in alternative cancer circles [1].
5
Hydrazine Sulfate
Hydrazine sulfate
BannedModerateRestricted
Clinical verdict: Hydrazine sulfate is a ROCKET FUEL COMPONENT and CARCINOGEN promoted as cancer treatment. Three NCI RCTs: NO benefit + INCREASED toxicity. IARC Group 2B carcinogen. Still promoted in alternative cancer networks despite definitive negative evidence. Patients taking rocket fuel for cancer based on debunked 1970s theory [1].
RDA
NOT a supplement — toxic industrial chemical
Target
N/A
UL
No safe dose
Category
Restricted
Population dosing
2 Risk self-assessment
DANGEROUS [1].
Select factors above to see your risk level
Clinical pearl for practitioners
SupplementIndex
Hydrazine Sulfate
Hydrazine sulfate · Banned · Evidence: Moderate
RDA
NOT a supplement — toxic industrial chemical
Upper limit
No safe dose
Evidence
Moderate
Clinical bottom line
Hydrazine sulfate is a ROCKET FUEL COMPONENT and CARCINOGEN promoted as cancer treatment. Three NCI RCTs: NO benefit + INCREASED toxicity. IARC Group 2B carcinogen. Still promoted in alternative cancer networks despite definitive negative evidence. Patients taking rocket fuel for cancer based on debunked 1970s theory [1].
Do not miss
⚠ DANGEROUS — see overview [1]
Pregnancy
ABSOLUTELY CONTRAINDICATED — carcinogen + hepato/neurotoxin [1].
4 Lab interpreter

See overview

<12 Deficient
12–20 Insufficient
20–50 Optimal
50–100 Excess
>150 Toxic
Your level:
Enter a value above
⚕ For healthcare professionals. Does not replace clinical judgment.
5 Quick facts
CategoryRestricted
Safety levelBanned
EvidenceModerate
RDANOT a supplement — toxic industrial chemical
Upper limit (UL)No safe dose
Scientific nameHydrazine sulfate
DANGEROUS/RESTRICTED — see overview[1]
6 Dosage by population

Adults Moderate

See product label

Elderly Moderate

See product label
Consider reduced renal/hepatic clearance. Start at lower end of range.

Pregnancy Moderate

See guidance
ABSOLUTELY CONTRAINDICATED — carcinogen + hepato/neurotoxin [1].

Pediatric Moderate

See guidance
ABSOLUTELY NOT [1].

Athletes Limited

Standard dose

Obesity Limited

Standard dose
Fat-soluble compounds may require dose adjustment in obesity.

Renal Limited

Consult specialist
Dose adjustment may be needed in renal impairment.

Vegan Moderate

Standard dose
DANGEROUS — NOT for supplementation. See overview [1].
7 Form comparison
FormBioavailabilityVeganCost/day
['See overview', 'restricted/banned', 'See overview [1].']StandardCheck label
8 Clinical evidence

Strong evidence

See overview [1]. HIGH

Moderate evidence

See overview [1]. MODERATE

Insufficient evidence

See overview [1]. LOW
9 Safety

🚩 Red flags — when to stop and refer

● DANGEROUS — see overview [1]

Pregnancy

ABSOLUTELY CONTRAINDICATED — carcinogen + hepato/neurotoxin [1].

Pediatric

ABSOLUTELY NOT [1].
10 Toxicity and overdose

11 Drug interactions
See overview Lethal/major
Mechanism: See overview [1].
Effect: See overview [1].
Action: DO NOT USE [1].
12 Supplement interactions
13 Laboratory monitoring
See overview Primary
Target: N/A · N/A
See overview [1].
14 Deficiency and prevalence
0%
[1]

Risk factors

• DANGEROUS [1].
15 Frequently asked questions
DANGER ▼
Hydrazine sulfate is a ROCKET FUEL COMPONENT and CARCINOGEN promoted as cancer treatment. Three NCI RCTs: NO benefit + INCREASED toxicity. IARC Group 2B carcinogen. Still promoted in alternative cancer networks despite definitive negative evidence. Patients taking rocket fuel for cancer based on debunked 1970s theory [1].
16 Regulatory status
BANNED/RESTRICTED — see overview: [1].
17 References
[1]See overview. REVIEW
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19 Cite this page
Vancouver
Pkhakadze G. Hydrazine Sulfate — safety profile [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 May 30]. Available from: https://supplement.ge/ingredients/hydrazine-sulfate/
APA 7th
Pkhakadze, G. (2026). Hydrazine Sulfate — Safety profile. Public Health Institute of Georgia. https://supplement.ge/ingredients/hydrazine-sulfate/
CC BY 4.0
🛡 SupplementIndex receives no funding from supplement manufacturers. All content independently authored by PHIG.
GP
Reviewed by Prof. G. Pkhakadze, MD, MPH, PhD
Editor-in-Chief, Georgian Medical Journal · Chair, PHIG
Last reviewed: May 2026 · Next: November 2026
This entry is provided for educational and public health purposes under CC BY 4.0. Consult your healthcare provider before starting any supplement. For corrections: info@accreditation.ge.
Publisher: PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD