SAFE
Willow Bark Salicin
Salix alba standardised 15% salicin
Possibly Safe
V1 Verified
Anti-inflammatory Herbs
PubMed Studies
1,400
About
Standardised willow bark (15% salicin) for aspirin-like anti-inflammatory and analgesic effects via salicylate mechanism.
How it works (mechanism of action)
Inhibits key inflammatory enzymes (COX-1/2, 5-LOX) or transcription factors (NF-kB, AP-1) reducing prostaglandin, leukotriene, and cytokine production. Some activate PPAR-gamma nuclear receptor mediating anti-inflammatory gene transcription.
👥 Safety by Population
🚫 Contraindications & Warnings
Aspirin allergy: cross-reactivity. Anticoagulant interaction. Not for children (Reye syndrome risk).
🏷️ Other Names
Salix alba standardised 15% salicin