SAFE

Glucosamine Sulphate

glucosamine-sulphate
Possibly Safe V1 Verified
Scan supplement →
Upper Safe Limit
Shellfish allergy (check source). May affect glucose tolerance. Anticoagulant interaction.
PubMed Studies
26
PubChem CID
About

Precursor for glycosaminoglycan synthesis in cartilage; reduces catabolic enzyme activity; mild anti-inflammatory

How it works (mechanism of action)

Very common in French pharmacy for osteoarthritis. EMA well-established use for symptomatic OA of knee. Arkopharma, Solgar, Pileje joint products. Often combined with chondroitin.

📊 Effectiveness
Knee osteoarthritis
Evidence Grade A · 20 studies · n=2,890 · Meta-analysis available
Possibly Effective
Osteoarthritis pain
Evidence Grade B · 42 studies · n=8,800
Possibly Effective

Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralLikely safe1500mg/day
ElderlyLikely safe1500mg/day
🚫 Contraindications & Warnings

Consult a healthcare professional before use if pregnant, breastfeeding, taking prescription medications, or if you have a medical condition. Keep out of reach of children.

🇪🇺 EU Health Claims Status
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food is not sufficiently defined to be able to be assessed and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(5)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed,this claimed effect for this food has not been substantiated
Regulation EU 1924/2006 · ART13 5
Products containing this ingredient (1)
Updated: 2026-04-02
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