⚠️
Major drug interaction. This ingredient has clinically significant drug interactions. See Drug Interactions below before use.
PubMed Studies
273
📊 Effectiveness
Blood pressure
Evidence Grade B · 22 studies · n=2,800
Cholesterol
Evidence Grade B · 28 studies · n=3,800
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Consult a healthcare professional before use if pregnant, breastfeeding, taking prescription medications, or if you have a medical condition. Keep out of reach of children.
💊 Drug Interactions (6)
🔴 Warfarin
MajorAnticoagulants
Management: Avoid high-dose supplements. Monitor INR. Food amounts generally safe.
🔴 Saquinavir / HIV PIs
MajorAntiretrovirals
Management: Contraindicated with saquinavir and HIV protease inhibitors.
🔴 Saquinavir
MajorAntiretroviral
Management: Avoid with saquinavir-based HIV therapy.
🟡 Aspirin / Clopidogrel
ModerateAntiplatelet drugs
Management: Use caution. Risk of excessive bleeding perioperatively.
⚪ ACE inhibitors
MinorAntihypertensives
Management: Monitor BP.
⚪ Insulin / Glipizide
MinorAntidiabetics
Management: Monitor blood glucose.
⚠️ Adverse Effects (1)
GI discomfort and breath/body odour
very common Mild
Gastrointestinal system
Allicin causes characteristic odour. Enteric-coated products reduce GI effects. No clinical significance.
🏷️ Other Names
Allium sativum
Garlic extract
Allicin
Aged garlic extract