SAFE

Fisetin

fisetin
Possibly Safe V1 Verified
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Upper Safe Limit
CYP3A4 inhibition at high doses. Insufficient pregnancy data.
PubMed Studies
7
PubChem CID
About

Flavonoid senolytic — selectively clears senescent cells; activates SIRT1; anti-inflammatory; neuroprotective; anti-glycation; extends lifespan in animal models

How it works (mechanism of action)

Emerging senolytic supplement in French anti-ageing market. Growing interest following Mayo Clinic research. Nat&Form, specialist longevity brands. Limited human trials.

📊 Effectiveness
Cognitive protection
Evidence Grade B · 6 studies · n=420
Possibly Effective

Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNo established UL
🚫 Contraindications & Warnings

Consult a healthcare professional before use if pregnant, breastfeeding, taking prescription medications, or if you have a medical condition. Keep out of reach of children.

Updated: 2026-04-02
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