SAFE

Epicatechin

Epicatechin dark chocolate catechin
Likely Safe V1 Verified Polyphenols
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PubMed Studies
140
PubChem CID
About

Catechin from cocoa and green tea with cardiovascular, myostatin-inhibiting, and mitochondrial effects.

How it works (mechanism of action)

Acts as direct free radical scavenger and indirect antioxidant via Nrf2/ARE pathway activation. Modulates inflammatory signalling via NF-kB and AP-1 inhibition. Interacts with kinase pathways (MAPK, PI3K/Akt, mTOR) and epigenetic regulators relevant to anti-ageing and disease prevention.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralLikely safeNot established
PregnancyLikely safeNot established
ElderlyLikely safeNot established
🚫 Contraindications & Warnings

Very safe at supplement doses. Anticoagulant interaction at very high doses.

🏷️ Other Names
Epicatechin dark chocolate catechin
Updated: 2026-04-11
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