⚠️
Major drug interaction. This ingredient has clinically significant drug interactions. See Drug Interactions below before use.
SAFE
Echinacea Angustifolia Root
Echinacea angustifolia standardised
Likely Safe
V1 Verified
Herbs and Botanicals
PubMed Studies
1
About
E. angustifolia root (alkylamides) with different bioactive profile from E. purpurea. Used for immune support.
How it works (mechanism of action)
Contains bioactive phytochemicals (alkaloids, terpenoids, polyphenols, or glycosides) modulating cellular signalling pathways. Primary mechanisms include enzyme inhibition, receptor modulation, and transcription factor activation relevant to documented clinical indications.
📊 Effectiveness
Common cold prevention
Evidence Grade B · 24 studies · n=1,840 · Meta-analysis available
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Autoimmune disease: avoid. Allergy to Asteraceae. Not for long-term continuous use.
💊 Drug Interactions (5)
🔴 Immunosuppressants
MajorImmunosuppressants
Management: AVOID in transplant patients and those on immunosuppressive therapy.
🔴 Cyclosporine / Tacrolimus
MajorImmunosuppressants
Management: Contraindicated in transplant patients. Risk of organ rejection.
🔴 Mitomycin / immunotherapy
MajorChemotherapy
Management: Consult oncologist. Avoid during immunosuppressive cancer treatment.
🟡 Docetaxel
ModerateChemotherapy
Management: Avoid during active chemotherapy.
⚪ Warfarin
MinorAnticoagulants
Management: Generally safe. Do not use >8 consecutive weeks.
🏷️ Other Names
Echinacea angustifolia standardised