SAFE
DPA
Docosapentaenoic acid (n-3 DPA)
Likely Safe
V1 Verified
Essential Fatty Acids
PubMed Studies
181
About
DPA (n-3) is an intermediate between EPA and DHA found in fish oil and seal oil. Has unique anti-inflammatory properties distinct from EPA and DHA.
How it works (mechanism of action)
Incorporated into cell membrane phospholipids altering membrane fluidity and lipid raft composition. Serve as precursors to specialised pro-resolving mediators (resolvins, protectins) that actively resolve inflammation. Activate PPAR nuclear receptors for metabolic gene transcription.
👥 Safety by Population
🚫 Contraindications & Warnings
Safe as part of omega-3 supplementation. Anticoagulant interaction.
🏷️ Other Names
Docosapentaenoic acid (n-3 DPA)