SAFE

Devil's Claw Root

Harpagophytum procumbens standardised
Possibly Safe V1 Verified Herbs & Botanicals
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PubMed Studies
1
About

Standardised devil's claw (3% harpagoside) for lower back pain, OA, and appetite stimulation. Commission E approved.

How it works (mechanism of action)

Contains bioactive phytochemicals (alkaloids, terpenoids, polyphenols, or glycosides) modulating cellular signalling pathways. Primary mechanisms include enzyme inhibition, receptor modulation, and transcription factor activation relevant to documented clinical indications.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Peptic ulcers: avoid. Anticoagulant interaction. Gallstones: consult physician. Cardiac arrhythmia: caution.

🏷️ Other Names
Harpagophytum procumbens standardised
Updated: 2026-04-11
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