SAFE

D-Mannose Powder

D-Mannose 2000mg powder
Possibly Safe V1 Verified Kidney Herbs
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PubMed Studies
2
About

D-Mannose at 2g twice daily shown effective for UTI prevention and treatment by blocking bacterial adhesion receptors.

How it works (mechanism of action)

Provides diuretic effects via prostaglandin-mediated renal blood flow increase. Anti-inflammatory activity reduces renal tubular inflammation. Antilithic effects may involve urine alkalinisation, citrate excretion, or dissolution of calcium oxalate crystals.

📊 Effectiveness
UTI prevention
Evidence Grade B · 12 studies · n=1,200
Possibly Effective

Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Generally very safe. Diarrhoea at very high doses. Blood sugar: theoretical concern in diabetes.

🏷️ Other Names
D-Mannose 2000mg powder
Updated: 2026-04-02
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