SAFE
Cycloastragenol
Cycloastragenol (telomerase activator)
Possibly Safe
V1 Verified
Adaptogens
PubMed Studies
1
PubChem CID
About
Astragalus saponin that activates telomerase, potentially slowing telomere shortening. Anti-ageing compound.
How it works (mechanism of action)
Modulates hypothalamic-pituitary-adrenal (HPA) axis and sympathoadrenal system to normalise physiological responses to stress. Activates heat shock proteins and stress-response pathways providing non-specific resistance to physical, chemical, and biological stressors.
📊 Effectiveness
Anti-ageing
Evidence Grade C · 3 studies · n=180
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Very limited human data. Generally well tolerated short-term. Theoretical oncology concerns.
🏷️ Other Names
Cycloastragenol (telomerase activator)