PubMed Studies
5
PubChem CID
About
Creatine with nitrate for combined creatine and nitric oxide ergogenic effects.
How it works (mechanism of action)
Enhances exercise performance via substrate provision, haemodynamic effects (vasodilation via nitric oxide), or anabolic/anti-catabolic signalling (mTOR activation). Reduces exercise-induced oxidative stress and inflammatory cytokine production.
📊 Effectiveness
Athletic performance
Evidence Grade B · 6 studies · n=480
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Less studied than monohydrate. Vasodilator drug interactions. Safe at supplement doses.
🏷️ Other Names
Creatine nitrate