SAFE
Cang Zhu
Atractylodes lancea (Sword-leaf atractylodes)
Possibly Safe
V1 Verified
TCM Herbs
PubMed Studies
880
About
Cang Zhu rhizome contains atractylodin and beta-eudesmol with damp-transforming, digestive, and anti-inflammatory effects. Used for damp-induced fatigue, joint pain, and digestive weakness.
How it works (mechanism of action)
Acts via multiple pharmacodynamic mechanisms consistent with Traditional Chinese Medicine polypharmacology. Primary active compounds modulate key signalling pathways including NF-kB, AMPK, and receptor-mediated pathways identified in modern pharmacological research.
📊 Effectiveness
Damp conditions and joint pain
Evidence Grade B · 6 studies · n=680
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Blood sugar-lowering interaction. Pregnancy: avoid. Drug metabolism: CYP450 effects.
🏷️ Other Names
Atractylodes lancea (Sword-leaf atractylodes)