CAU
Calcitriol
1,25-Dihydroxyvitamin D3 (active form)
Use with Caution
V2 Verified
Vitamins & Cofactors
PubMed Studies
615
PubChem CID
About
Active hormonal form of Vitamin D. Used pharmaceutically for secondary hyperparathyroidism in CKD and hypoparathyroidism. Supplement use INAPPROPRIATE — very narrow therapeutic index.
How it works (mechanism of action)
Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.
👥 Safety by Population
🚫 Contraindications & Warnings
PRESCRIPTION ONLY: Too potent for unsupervised supplement use. Narrow therapeutic index — hypercalcaemia and hypercalciuria risk at very small dose increases. Monitoring of serum calcium essential. NOT for supplement use.
🏷️ Other Names
1,25-Dihydroxyvitamin D3 (active form)