SAFE

Borage Seed Oil

Borago officinalis seed oil
Possibly Safe V1 Verified Essential Fatty Acids
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PubMed Studies
7
About

Borage oil is the richest plant source of GLA (24%). Used for eczema, PMS, RA, and anti-inflammatory support.

How it works (mechanism of action)

Incorporated into cell membrane phospholipids altering membrane fluidity and lipid raft composition. Serve as precursors to specialised pro-resolving mediators (resolvins, protectins) that actively resolve inflammation. Activate PPAR nuclear receptors for metabolic gene transcription.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Pyrrolizidine alkaloid (PA) free forms only safe. Anticoagulant interaction. Pregnancy: avoid. Epilepsy: caution.

🏷️ Other Names
Borago officinalis seed oil
Updated: 2026-04-11
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