PubMed Studies
4,800
About
Branched-chain amino acids (leucine, isoleucine, valine in 2:1:1 ratio). Used for muscle protein synthesis, exercise recovery, and anti-catabolism.
How it works (mechanism of action)
Serves as building block for protein synthesis or direct precursor for neurotransmitters, hormones, and enzymatic cofactors. Participates in nitrogen metabolism, energy production, and cellular signalling pathways relevant to studied health outcomes.
📊 Effectiveness
Muscle recovery
Evidence Grade B · 18 studies · n=2,200
Exercise performance
Evidence Grade B · 14 studies · n=1,400
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Very safe. GI side effects at very high doses. ALS risk signal: one epidemiological study; not confirmed.
Products containing this ingredient (1)
Kazuya Amino Acid Complex
3000 MG Tablet
🏷️ Other Names
Leucine / Isoleucine / Valine