Atropa belladonna
Deadly nightshade containing tropane alkaloids atropine, scopolamine, and hyoscyamine — potent anticholinergic agents. Pharmaceutical-grade preparations exist for specific medical indications. As an unregulated supplement the alkaloid content is highly variable making it extremely dangerous.
How it works (mechanism of action)
Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.
DANGEROUS: therapeutic window extremely narrow. Anticholinergic toxidrome: dry mouth, urinary retention, tachycardia, mydriasis, hyperthermia, delirium, seizures, coma, death. Contraindicated in glaucoma, BPH, myasthenia gravis, cardiac disease. Drug interactions: antihistamines, antipsychotics, tricyclic antidepressants. NOT permitted as food supplement.