SAFE
Atractylodes Macrocephala
Atractylodes macrocephala Bai Zhu
Likely Safe
V1 Verified
TCM Herbs
PubMed Studies
5
About
Bai Zhu rhizome is a primary TCM spleen qi tonic containing atractylenolides. Used for digestive weakness, fatigue, fluid retention, and immune support.
How it works (mechanism of action)
Acts via multiple pharmacodynamic mechanisms consistent with Traditional Chinese Medicine polypharmacology. Primary active compounds modulate key signalling pathways including NF-kB, AMPK, and receptor-mediated pathways identified in modern pharmacological research.
📊 Effectiveness
Digestive weakness and immune support
Evidence Grade B · 8 studies · n=880
Digestive health
Evidence Grade C · 6 studies · n=380
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Generally well tolerated. Blood sugar-lowering effect. Drug interaction: CYP450 modulation.
🏷️ Other Names
Atractylodes macrocephala Bai Zhu