SAFE

Astragalus Membranaceus

Astragalus membranaceus root standardised
Likely Safe V1 Verified Adaptogens
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PubMed Studies
52
About

Standardised root extract with polysaccharides, saponins, and cycloastragenol. Premier TCM immunomodulator.

How it works (mechanism of action)

Modulates hypothalamic-pituitary-adrenal (HPA) axis and sympathoadrenal system to normalise physiological responses to stress. Activates heat shock proteins and stress-response pathways providing non-specific resistance to physical, chemical, and biological stressors.

📊 Effectiveness
Immune function
Evidence Grade A · 22 studies · n=3,800 · Meta-analysis available
Likely Effective

Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralLikely safeNot established
PregnancyLikely safeNot established
ElderlyLikely safeNot established
🚫 Contraindications & Warnings

Autoimmune conditions: caution. Immunosuppressant interaction.

🏷️ Other Names
Astragalus membranaceus root standardised
Updated: 2026-04-11
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