SAFE
Alpha-galactosidase
Alpha-galactosidase
Likely Safe
V4 Verified
Digestive Health
Upper Safe Limit
No UL established
PubMed Studies
107
About
Alpha-galactosidase (Beano) breaks down raffinose-family carbohydrates in legumes and cruciferous vegetables that humans cannot digest, reducing gas and bloating.
How it works (mechanism of action)
Hydrolyses alpha-1,6-galactosidic bonds in RFOs (raffinose, stachyose) found in beans and vegetables that would otherwise be fermented by colonic bacteria producing gas.
📊 Effectiveness
Gas and bloating from legumes
Evidence Grade A · 18 studies · n=2,800 · Meta-analysis available
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Very safe. Diabetics: improves carbohydrate digestion, may slightly raise blood sugar from vegetable carbs.