SAFE

Aloe Vera

aloe-vera
Possibly Safe V1 Verified
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Upper Safe Limit
Oral anthraquinone form contraindicated in pregnancy — laxative/uterine stimulant
PubMed Studies
142
PubChem CID
About

Polysaccharides (acemannan) modulate immune response; anti-inflammatory; wound healing promotion

How it works (mechanism of action)

Topical: widely used for burns, dermatitis and wound healing. Oral: used for constipation and IBS. Very common French pharmacy.

📊 Effectiveness
Constipation
Evidence Grade A · 18 studies · n=2,200 · Meta-analysis available
Effective
IBS symptoms
Evidence Grade B · 12 studies · n=1,200
Possibly Effective
Blood sugar control
Evidence Grade B · 14 studies · n=1,400
Possibly Effective

Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Consult a healthcare professional before use if pregnant, breastfeeding, taking prescription medications, or if you have a medical condition. Keep out of reach of children.

💊 Drug Interactions (4)
🟡 Antidiabetic drugs
Moderate
Antidiabetic
Management: Monitor blood glucose.
🟡 Digoxin
Moderate
Cardiac glycoside
Management: Monitor potassium and digoxin levels.
🟡 Diuretics
Moderate
Diuretic
Management: Monitor electrolytes.
⚪ Warfarin
Minor
Anticoagulant
Management: Monitor INR.
Updated: 2026-04-11
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