1 Product identity
Ingredient risk
Contains a high-risk ingredient
LipidOptimal
BrandKaruna→Other Combinations Capsule 11 ingredients 1 high-risk 2 caution DSLD #24500Net contents: 180 Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2013-08-23
2 Ingredients (11)
IngredientGroupSafety
PantethinePantethine—
KudzuKudzu —
Gelatin Capsulecapsule—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Inositol — GDM prevention — 4 g/day from first trimester in high-risk women [2]
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Chromium — Conditionally Safe
⚠ Hypoglycemia with diabetes meds
⚠ Rare renal/hepatic toxicity
Inositol — High risk
⚠ GI disturbance at high doses (>12 g)
⚠ May lower blood glucose
Oyster Mushroom — Generally Safe
⚠ Generally well tolerated
⚠ May lower cholesterol and blood glucose
Garlic Extract — Limited Evidence
⚠ Increased bleeding risk
⚠ GI upset
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Magnesium — Use with Caution
4 Label claims
• All Other
5 Data source
DSLD ID24500
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2013-08-23
6 More from Karuna
View Karuna Safety Scorecard → 86 products
5-HTP 100 mg5-HTP 100 mgAllerEzeAlpha Lipoic Acid 100 mgB-12 LiquidBromeZyme7 Cite this page
Vancouver
Pkhakadze G. LipidOptimal — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 27]. Available from: https://academy.gmj.ge/products/lipidoptimal-24500/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG