1 Product identity
Ingredient risk
Contains a high-risk ingredient
Life's Essentials Plus
BrandVitabase→Other Combinations Tablet or Pill 91 ingredients 1 high-risk 6 caution DSLD #7437Net contents: 90 Tablet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2012-04-26
2 Ingredients (91)
IngredientGroupSafety
Vegetable Complex (Herb/Botanical)Blend (Herb/Botanical)—
BroccoliBroccoli—
Celerycelery—
ParsleyParsley—
CauliflowerCauliflower —
CarrotsCarrot —
YamsYam (unspecified)—
Collard GreensCollard—
KaleKale—
Brussel SproutsBrussel Sprout—
Fruit Complex (Herb/Botanical)Blend (Herb/Botanical)—
OrangesOrange (unspecified)—
LemonsLemon—
TangerinesTangerine—
GrapefruitsGrapefruit—
LimesLime—
Citrus BioflavonoidsFlavonoid (mixture)—
AcidophilusLactobacillus acidophilus—
Soy Isoflavonesisoflavone (unspecified)—
Mushroom Complex (Non-Nutrient/Non-Botanical)Blend (non-nutrient/non-botanical)—
ShiitakeShiitake Mushroom—
Para-Aminobenzoic AcidPABA—
Hesperidin ComplexBlend (non-nutrient/non-botanical)—
RutinRutin—
RNA/DNA ComplexBlend (non-nutrient/non-botanical)—
RNARNA—
DNADNA—
PinePine—
Siberian GinsengEleuthero—
Flaxseed powderFlaxseed—
Oat BranOat Fiber—
Digestive Enzyme ComplexBlend—
CellulaseCellulase—
TrypsinTrypsin—
LipaseLipase—
AmylaseAmylase—
Trace Mineral ComplexBlend (Combination)—
Proprietary BlendProprietary Blend (Combination)—
Lecithinlecithin—
Yellow Dock——
GarlicGarlic—
LicoriceLicorice —
Stearic AcidStearic Acid—
Microcrystalline CelluloseCellulose—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Inositol — GDM prevention — 4 g/day from first trimester in high-risk women [2]
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin A — Conditionally Safe
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Vitamin K — Limited Evidence
⚠ Critical interaction with warfarin
Thiamin — Use with Caution
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Pantothenic Acid — Generally Safe
⚠ Diarrhea at very high doses
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Phosphorus — Generally Safe
⚠ Excess impairs calcium absorption
Iodine — Conditionally Safe
⚠ Thyroid dysfunction at excess
⚠ Kelp: variable content
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Selenium — Conditionally Safe
⚠ Selenosis >400 mcg
⚠ Diabetes risk at high doses
Copper — Conditionally Safe
⚠ Hepatotoxicity at high doses
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Chromium — Conditionally Safe
⚠ Hypoglycemia with diabetes meds
⚠ Rare renal/hepatic toxicity
Molybdenum — Generally Safe
⚠ Very low toxicity
Potassium — Conditionally Safe
⚠ Hyperkalemia risk
⚠ Dangerous with ACE inhibitors
Chloride — Generally Safe
⚠ Co-ingested with sodium
NAC — Limited Evidence
⚠ GI upset
⚠ Rare bronchospasm
Spirulina — Limited Evidence
⚠ Contamination risk: microcystins, heavy metals
⚠ Autoimmune stimulation
Reishi — Limited Evidence
⚠ Hepatotoxicity (rare, powdered form)
⚠ Antiplatelet effect
Maitake — Limited Evidence
⚠ May lower blood glucose
⚠ May lower blood pressure
Quercetin — Conditionally Safe
⚠ Inhibits CYP3A4
⚠ Affects cyclosporine levels
Choline — Generally Safe
⚠ Fishy odor at high doses
Inositol — High risk
⚠ GI disturbance at high doses (>12 g)
⚠ May lower blood glucose
Boron — Conditionally Safe
⚠ Reproductive toxicity in animals
Lutein — Generally Safe
⚠ Harmless skin yellowing at very high doses
Coenzyme Q10 — Limited Evidence
⚠ May reduce warfarin efficacy
⚠ Mild GI effects
Grape Seed Extract — Limited Evidence
⚠ Antiplatelet effect
⚠ May interact with anticoagulants
Green Tea Extract — Limited Evidence
⚠ HEPATOTOXICITY >800 mg EGCG
⚠ Iron absorption inhibition
Barley Grass — Limited Evidence
⚠ Celiac: grass should be gluten-free but contamination possible
⚠ GI discomfort
Panax Ginseng — Limited Evidence
⚠ Insomnia
⚠ Estrogenic effects
Betaine HCl — Limited Evidence
⚠ Heartburn, GI burning if used without protein meals
⚠ Not for those on H. pylori treatment
Papain — Conditionally Safe
⚠ Allergic reactions
⚠ Increased bleeding risk
Bromelain — Conditionally Safe
⚠ Increased bleeding risk
⚠ GI upset
Ginkgo Biloba — Limited Evidence
⚠ BLEEDING RISK
⚠ Seizures (ginkgotoxin)
bilberry — Generally Safe
⚠ May increase bleeding risk at high doses
⚠ May lower blood glucose
Gotu Kola — Conditionally Safe
⚠ Hepatotoxicity (rare)
⚠ Drowsiness
Apple Pectin — Limited Evidence
⚠ Gas, bloating
⚠ May reduce medication absorption
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID7437
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2012-04-26
6 More from Vitabase
View Vitabase Safety Scorecard → 264 products
Acai BerryAcetyl L-CarnitineAcid ComfortAcid ReduxAcidophilusAcidophilus7 Cite this page
Vancouver
Pkhakadze G. Life's Essentials Plus — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 27]. Available from: https://academy.gmj.ge/products/dsld-7437/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG