1 Product identity
Ingredient risk
Contains restricted ingredients
Women's Ultra Mega
BrandGNC Women's Ultra Mega→Other Combinations Other (e.g. tea bag) 68 ingredients 2 banned 1 high-risk 7 caution DSLD #63221Net contents: 28 Caplet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2016-07-25
2 Ingredients (68)
IngredientGroupSafety
Super Antioxidant Blend (Combination)Blend (Combination)—
LycopeneLycopene—
ZeaxanthinZeaxanthin—
Beta-CryptoxanthinCryptoxanthin—
Fruit & Vegetable BlendBlend (Herb/Botanical)—
Orange peel powderOrange (unspecified)—
Acai fruit powderAcai—
Blueberry pomace powderBlueberry—
Cranberry fruit powdercranberry—
Pomegranate fruit powderPomegranate—
Broccoli powderBroccoli—
Tomato powderTomato—
Grape skin powderGrape —
Carrot powderCarrot —
Papaya fruit powderPapaya—
Pineapple fruit powderPineapple—
Cauliflower powderCauliflower —
Kale leaf powderKale—
Apple fruit powderApple—
Kiwi fruit powderKiwi—
Beauty BlendBlend—
Green Tea leaf extractGreen Tea—
Brain Health BlendBlend (Combination)—
CelluloseCellulose—
Stearic AcidStearic Acid—
natural Vanilla Mint flavorFlavor—
ChlorophyllChlorophyll—
Stevia leaf extractStevia—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Inositol — GDM prevention — 4 g/day from first trimester in high-risk women [2]
⛔ Contains an ingredient banned in ≥1 country
GABA 🇺🇸 🇯🇵 — ates (FDA) :: Dietary supplement. Picamilon (GABA + niacin) banned as supplement (2015) [1]. || Japan :: GABA is a popular functional food i
Titanium Dioxide 🇫🇷 🇪🇺 — France banned TiO₂ in food from January 2020, first EU country.
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Iron — Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin A — Conditionally Safe
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Vitamin K — Conditionally Safe
⚠ Critical interaction with warfarin
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Pantothenic Acid — Limited Evidence
⚠ Diarrhea at very high doses
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Iron — Use with Caution
⚠ GI upset, constipation
⚠ Fatal toxicity in children
Iodine — Conditionally Safe
⚠ Thyroid dysfunction at excess
⚠ Kelp: variable content
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Selenium — Conditionally Safe
⚠ Selenosis >400 mcg
⚠ Diabetes risk at high doses
Copper — Conditionally Safe
⚠ Hepatotoxicity at high doses
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Chromium — Conditionally Safe
⚠ Hypoglycemia with diabetes meds
⚠ Rare renal/hepatic toxicity
Molybdenum — Generally Safe
⚠ Very low toxicity
Alpha-Lipoic Acid — Limited Evidence
⚠ May lower blood glucose
⚠ May lower thyroid hormones
Lutein — Generally Safe
⚠ Harmless skin yellowing at very high doses
Astaxanthin — Generally Safe
⚠ May lower blood pressure
NAC — Limited Evidence
⚠ GI upset
⚠ Rare bronchospasm
Elderberry — Limited Evidence
⚠ Raw berries: cyanogenic glycosides
⚠ Cytokine storm concern
Silicon — Generally Safe
⚠ Very low toxicity
Hyaluronic acid — Generally Safe
⚠ Generally well tolerated
⚠ Theoretical concern in active cancer (promotes angiogenesis)
Grape Seed Extract — Limited Evidence
⚠ Antiplatelet effect
⚠ May interact with anticoagulants
Choline — Generally Safe
⚠ Fishy odor at high doses
Inositol — High risk
⚠ GI disturbance at high doses (>12 g)
⚠ May lower blood glucose
Boron — Conditionally Safe
⚠ Reproductive toxicity in animals
GABA — Banned in ≥1 country
⚠ Drowsiness
⚠ May enhance sedatives
Vanadium — Limited Evidence
⚠ GI toxicity: nausea, vomiting, diarrhea
⚠ Green tongue
Titanium Dioxide — Banned in ≥1 country
⚠ EFSA: can no longer be considered safe as food additive (2021)
⚠ Genotoxicity concern (nanoparticles)
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID63221
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2016-07-25
6 More from GNC Women's Ultra Mega
View GNC Women's Ultra Mega Safety Scorecard → 53 products
50 Plus50 Plus MiniBlood Glucose SupportBurn 60Calcium & Vitamin D With MBPCalcium 5007 Cite this page
Vancouver
Pkhakadze G. Women's Ultra Mega — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 27]. Available from: https://academy.gmj.ge/products/dsld-63221/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG