1 Product identity
Ingredient risk
7 ingredients to use with caution
Estrium Natural Tropical Mango Flavor
BrandMetagenics→Other Combinations Powder 69 ingredients 7 caution DSLD #26809Net contents: 23 oz.
Target: Adults and Children 4 years and above
DSLD entry: 2013-10-25
2 Ingredients (69)
IngredientGroupSafety
CaloriesCalories—
FatFat (unspecified)—
Saturated FatSaturated fat—
Trans FatTrans fat—
CholesterolCholesterol—
Total CarbohydratesCarbohydrate—
Dietary FiberFiber (unspecified)—
SugarSugar—
ProteinProtein (unspecified)—
L-ThreonineTHREONINE—
Isoflavonesisoflavone (unspecified)—
FlaxseedFlax—
70 mg of flax lignansLignan (unspecified)—
Rice syrup solidsRice—
FructoseFructose—
Olive OilOlive Oil—
flaxseedFlax—
Natural flavorsFlavor—
Xanthan GumXanthan Gum—
curcumin powderCurcumin—
Guar GumGuar—
pueraria root extractKudzu —
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Iron — Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Sodium — Conditionally Safe
⚠ Hypertension
⚠ Fluid retention
Potassium — Conditionally Safe
⚠ Hyperkalemia risk
⚠ Dangerous with ACE inhibitors
Vitamin A — Conditionally Safe
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Iron — Use with Caution
⚠ GI upset, constipation
⚠ Fatal toxicity in children
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Pantothenic Acid — Limited Evidence
⚠ Diarrhea at very high doses
Phosphorus — Generally Safe
⚠ Excess impairs calcium absorption
Iodine — Conditionally Safe
⚠ Thyroid dysfunction at excess
⚠ Kelp: variable content
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Copper — Conditionally Safe
⚠ Hepatotoxicity at high doses
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Chromium — Conditionally Safe
⚠ Hypoglycemia with diabetes meds
⚠ Rare renal/hepatic toxicity
L-Lysine — Limited Evidence
⚠ GI discomfort at high doses
⚠ May increase calcium absorption
Choline — Generally Safe
⚠ Fishy odor at high doses
Rice Protein — Generally Safe
⚠ Lower in lysine
⚠ Arsenic contamination risk in some brands
4 Label claims
• All Other
5 Data source
DSLD ID26809
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2013-10-25
6 More from Metagenics
View Metagenics Safety Scorecard → 118 products
ActiFolateAdvaClearArginine PlusAxis Endo Mango FlavorAzeo-PangenAzeo-Pangen7 Cite this page
Vancouver
Pkhakadze G. Estrium Natural Tropical Mango Flavor — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 27]. Available from: https://academy.gmj.ge/products/dsld-26809/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG