✓ No active regulatory warningsFDA MedWatch, EMA EudraVigilance, WHO VigiBase, WADA Prohibited List · 2026-05-29
📰Read the full Schisandra Berry evidence review on GMJ News →Complete clinical article, references and updates on news.gmj.ge. This page is the structured safety summary.⚠ Full data under 'Schisandra' entry [1]
⚠ CYP3A4 interaction with tacrolimus is documented, not theoretical [1]
ℹ️ Not obtained from food. Not applicable — this is not obtained from food in meaningful amounts; supplementation is the practical route.
🔬 Lab interpreter
Recommended test
See Schisandra
See Schisandra
Reference range / target
N/A
N/A
When to test
N/A
N/A
See main entry [1].
Full lab monitoring ↓⚕ For professionals — confirm ranges against your local laboratory.
Clinical verdict
Alternate name entry. See 'Schisandra' for complete data. Critical: CYP3A4 inhibition is DOCUMENTED (tacrolimus interaction) [1].
1 How much do I need?
👤 Adults: Specific dosage data under clinical review
👴 Elderly: Specific dosage data under clinical review
🤰 Pregnancy: See guidance
See Schisandra entry [1].
👦 Pediatric: See guidance
See Schisandra entry [1].
🏃 Athletes: Standard dose
⚖️ Obesity: Standard dose
Fat-soluble compounds may require dose adjustment in obesity.
🩺 Renal: Consult specialist
Dose adjustment may be needed in renal impairment.
🌱 Vegan: Standard dose
How to take
🍽 Timing: See Schisandra [1].
💊 With food: See main entry [1].
🚫 Avoid: CYP3A4 drugs without monitoring [1].
2 Which form?
| Form | Bioavailability | Vegan | Cost |
|---|---|---|---|
| ['See Schisandra entry', 'complete', 'Full forms and dosing in main entry [1].'] | Standard | Check label |
3 Common questions
Where is the full data? ▼
See 'Schisandra' entry for complete clinical data [1].
4 Clinical evidence
Strong
See Schisandra entry [1]. HIGH
Moderate
See Schisandra entry [1]. MODERATE
Insufficient
See Schisandra entry [1]. LOW
5 Safety, toxicity & adverse events
Absolute contraindications
✕ Pregnancy — may stimulate the uterus
Relative
⚠ Induces CYP3A4/CYP2C9 — can alter levels of many drugs
⚠ Epilepsy or peptic ulcer — traditional cautions
⚠ (Same botanical as 'Schisandra')
🚩 Red flags
● Transplant patient using Schisandra berry — tacrolimus interaction [1]
6 Interactions
Drug interactions
7 Regulatory
See Schisandra entry: Chinese Pharmacopoeia, Russian Pharmacopoeia, EMA [1].
8 Cite this page
Vancouver: Pkhakadze G. Schisandra Berry — safety profile [Internet]. Tbilisi: PHIG; 2026 [cited 2026 Aug 15]. Available from: https://supplement.ge/ingredients/schisandra-berry/
APA 7th: Pkhakadze, G. (2026). Schisandra Berry — Safety profile. Public Health Institute of Georgia. https://supplement.ge/ingredients/schisandra-berry/
📋 Editorial information
Author: Prof. G. Pkhakadze, MD, MPH, PhD
Institution: Public Health Institute of Georgia (PHIG)
Affiliation: David Tvildiani Medical University (DTMU)
First published: January 2026
Last reviewed: 2026-05-29
Next review: February 2027
References: 1 cited sources
COI: SupplementIndex receives no funding from supplement manufacturers. All content independently authored by PHIG.
Process: Systematic literature review
📄 License & reuse
Published under Creative Commons Attribution 4.0 International (CC BY 4.0). You may share and adapt for any purpose with attribution.
Pkhakadze G. "Schisandra Berry — Safety Profile." SupplementIndex, PHIG, 2026. https://supplement.ge/ingredients/schisandra-berry/ CC BY 4.0.
GP
Prof. G. Pkhakadze, MD, MPH, PhD
Professor of Public Health · Head of Department, DTMU
Editor-in-Chief, Georgian Medical Journal (ISSN 3088-4322)
Chair, Public Health Institute of Georgia · UEMS Public Health Section
Educational and public health purposes. CC BY 4.0. Consult your healthcare provider before starting any supplement. Corrections: info@accreditation.ge. Publisher: PHIG