PubMed Studies
280
About
Gravel root (Joe Pye weed) contains euparin and flavonoids with diuretic and antilithic effects for kidney stones and urinary infections.
How it works (mechanism of action)
Provides diuretic effects via prostaglandin-mediated renal blood flow increase. Anti-inflammatory activity reduces renal tubular inflammation. Antilithic effects may involve urine alkalinisation, citrate excretion, or dissolution of calcium oxalate crystals.
👥 Safety by Population
🚫 Contraindications & Warnings
Pyrrolizidine alkaloids: ensure PA-free preparation. Pregnancy: avoid.
🏷️ Other Names
Eupatorium purpureum