SAFE

Glycosaminoglycans

GAG complex (HA, chondroitin, dermatan, heparan sulfate)
Possibly Safe V2 Verified Specialty Bioactives
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PubMed Studies
164
About

Family of sulphated polysaccharides forming the extracellular matrix. Includes hyaluronic acid, chondroitin sulfate, dermatan sulfate, heparan sulfate, and keratan sulfate. Supplement use for joint and skin health.

How it works (mechanism of action)

Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Anticoagulant potential (structural similarity to heparin). Source allergen (bovine, porcine, marine). Warfarin interaction for sulphated GAG products. Generally well tolerated.

🏷️ Other Names
GAG complex (HA, chondroitin, dermatan, heparan sulfate)
Updated: 2026-04-11
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