SAFE
Glycine Sleep
Glycine 3000mg sleep formula
Likely Safe
V1 Verified
Sleep Support
PubMed Studies
2,200
About
Glycine at 3g before bed shown in Japanese RCTs to improve sleep quality, reduce fatigue, and improve cognitive performance next day.
How it works (mechanism of action)
Modulates GABAergic neurotransmission via GABA-A receptor allosteric modulation or GABA transaminase inhibition increasing inhibitory CNS tone. Activates melatonin synthesis or MT1/MT2 receptor pathways, or reduces cortisol secretion by modulating HPA axis activation.
👥 Safety by Population
🚫 Contraindications & Warnings
Very safe. Mild antispasmodic. No significant drug interactions at supplement doses.
🏷️ Other Names
Glycine 3000mg sleep formula