Upper Safe Limit
Generally considered safe at culinary doses; avoid high medicinal doses in first trimester
PubMed Studies
284
PubChem CID
About
Gingerols and shogaols act on 5-HT3 receptors and gastric motility; anti-inflammatory via COX inhibition
How it works (mechanism of action)
Used for nausea, vomiting and motion sickness. Excellent evidence base. Very common in French pharmacies. EMA well-established.
📊 Effectiveness
Nausea
Evidence Grade A · 28 studies · n=4,400 · Meta-analysis available
Knee osteoarthritis
Evidence Grade B · 7 studies · n=440
Inflammation
Evidence Grade B · 18 studies · n=2,200
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Consult a healthcare professional before use if pregnant, breastfeeding, taking prescription medications, or if you have a medical condition. Keep out of reach of children.
💊 Drug Interactions (1)
🟡 Warfarin
ModerateAnticoagulants
Management: Monitor INR. Limit ginger supplement dose to <4g/day with anticoagulants.
🏷️ Other Names
Zingiber officinale
Ginger root
Ginger extract
