Upper Safe Limit
Avoid high doses in pregnancy — oestrogenic; not for infants under 4 weeks
PubMed Studies
28
PubChem CID
About
Trans-anethole stimulates GI motility; antispasmodic; mild oestrogenic activity
How it works (mechanism of action)
Used for bloating, flatulence and infant colic. Very common in French pharmacies. EMA well-established use.
📊 Effectiveness
Digestive health
Evidence Grade B · 10 studies · n=880
IBS symptoms
Evidence Grade C · 8 studies · n=580
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Consult a healthcare professional before use if pregnant, breastfeeding, taking prescription medications, or if you have a medical condition. Keep out of reach of children.