CAU
FD&C Blue No. 2
Indigotine (E132)
Use with Caution
V2 Verified
Excipients & Additives
PubMed Studies
120
PubChem CID
About
Synthetic indigoid dye (indigo carmine) used as blue-purple food colouring. May cause allergic reactions in aspirin-sensitive individuals. Not included in EU mandatory hyperactivity label (unlike other Southampton Six dyes). Generally considered low toxicity at approved use levels.
How it works (mechanism of action)
Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.
👥 Safety by Population
🚫 Contraindications & Warnings
Potential allergic reactions in aspirin-sensitive individuals. Large doses may affect mucosal health. Generally low risk at approved food/supplement use levels. Not subject to EU hyperactivity labelling requirement. Monitor for allergic reactions.
🏷️ Other Names
Indigotine (E132)