SAFE

Eugenol

4-Allyl-2-methoxyphenol
Possibly Safe V2 Verified Excipients & Additives
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PubMed Studies
169
PubChem CID
About

Primary phenylpropanoid of clove oil. Used as dental analgesic (ZOE cement), flavouring, and antimicrobial. Hepatotoxic at high doses. Anticoagulant properties.

How it works (mechanism of action)

Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Hepatotoxicity: dose-dependent. Anticoagulant: avoid with warfarin and antiplatelet drugs. Dental sensitisation: contact allergy with prolonged dental use. Genotoxicity: conflicting data at high doses. Generally safe at food flavouring quantities.

Updated: 2026-04-11
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