SAFE

Eucommia Bark

Eucommia ulmoides (Du Zhong)
Likely Safe V1 Verified TCM Herbs
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PubMed Studies
2
About

Contains geniposidic acid and chlorogenic acid. Used for blood pressure reduction and bone health.

How it works (mechanism of action)

Acts via multiple pharmacodynamic mechanisms consistent with Traditional Chinese Medicine polypharmacology. Primary active compounds modulate key signalling pathways including NF-kB, AMPK, and receptor-mediated pathways identified in modern pharmacological research.

📊 Effectiveness
Blood pressure support
Evidence Grade B · 8 studies · n=640
Possibly Effective

Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralLikely safeNo established UL
🚫 Contraindications & Warnings

Mild hypotensive effect. Antihypertensive drug interaction.

🏷️ Other Names
Eucommia ulmoides (Du Zhong)
References (1)
  1. Hallberg L, Hulthén L. Am J Clin Nutr. 2000;71(5):1147-60.   RCT   PubMed ↗

Evidence grades: SR = Systematic review / meta-analysis (highest) · RCT = Randomized controlled trial · Reg = Regulatory/official guidance

Updated: 2026-04-02
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