SAFE
Ellagitannins
Ellagitannins pomegranate berry tannins
Likely Safe
V1 Verified
Polyphenols
PubMed Studies
31
About
Hydrolysable tannins from pomegranate, berries, and walnuts. Precursors to urolithin A via gut bacteria metabolism.
How it works (mechanism of action)
Acts as direct free radical scavenger and indirect antioxidant via Nrf2/ARE pathway activation. Modulates inflammatory signalling via NF-kB and AP-1 inhibition. Interacts with kinase pathways (MAPK, PI3K/Akt, mTOR) and epigenetic regulators relevant to anti-ageing and disease prevention.
👥 Safety by Population
🚫 Contraindications & Warnings
Very safe. Bioavailability depends on gut microbiome for urolithin production.
🏷️ Other Names
Ellagitannins pomegranate berry tannins