SAFE
Du Huo
Angelica pubescens (Hairy angelica root)
Possibly Safe
V1 Verified
TCM Herbs
PubMed Studies
880
About
Du Huo root contains osthole and bergapten with anti-inflammatory, analgesic, and antirheumatic effects. Used for lower back pain and rheumatic joint conditions.
How it works (mechanism of action)
Acts via multiple pharmacodynamic mechanisms consistent with Traditional Chinese Medicine polypharmacology. Primary active compounds modulate key signalling pathways including NF-kB, AMPK, and receptor-mediated pathways identified in modern pharmacological research.
👥 Safety by Population
🚫 Contraindications & Warnings
Photosensitivity (furanocoumarins). Allergy to Apiaceae. Blood pressure: mild lowering.
🏷️ Other Names
Angelica pubescens (Hairy angelica root)