SAFE

Dihydrolipoic acid

Dihydrolipoic acid (DHLA) — reduced form of ALA
Possibly Safe V2 Verified Specialty Bioactives
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PubMed Studies
1
PubChem CID
About

Reduced form of alpha-lipoic acid. Endogenously generated from ALA by lipoamide dehydrogenase. More potent antioxidant than oxidised ALA. Generally taken as ALA which converts to DHLA in vivo.

How it works (mechanism of action)

Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

See alpha-lipoic acid. As direct supplement limited data. Antioxidant properties similar. Hypoglycaemia risk.

🏷️ Other Names
Dihydrolipoic acid (DHLA) — reduced form of ALA
Updated: 2026-04-11
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