SAFE
D-Ribose Energy
D-Ribose 5000mg energy formula
Possibly Safe
V1 Verified
Energy Herbs
PubMed Studies
1,200
About
D-Ribose for cardiac energy metabolism, ATP resynthesis, chronic fatigue syndrome, and fibromyalgia support.
How it works (mechanism of action)
Activates mitochondrial biogenesis and electron transport chain efficiency via AMPK/PGC-1alpha pathway. Modulates adenosine receptors or phosphodiesterase to regulate cellular cAMP/cGMP energy signalling. Normalises adrenal cortisol and catecholamine responses to physical and psychological stress.
📊 Effectiveness
Chronic fatigue and cardiac energy
Evidence Grade B · 8 studies · n=800
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Generally safe. Blood sugar: may lower slightly. Diarrhoea at high doses.
🇪🇺 EU Health Claims Status
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
🏷️ Other Names
D-Ribose 5000mg energy formula