SAFE
Cyanocobalamin
Cyanocobalamin (synthetic B12)
Possibly Safe
V2 Verified
Vitamins & Cofactors
PubMed Studies
101
PubChem CID
About
Synthetic B12 form most studied in clinical trials. Converted to active forms (methylcobalamin, adenosylcobalamin). Contains small cyanide moiety.
How it works (mechanism of action)
Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.
👥 Safety by Population
🚫 Contraindications & Warnings
Leber disease/hereditary optic neuropathy: cyanocobalamin CONTRAINDICATED — cyanide component impairs mitochondrial function in this condition. Use methylcobalamin instead. Tobacco amblyopia: same caution. Otherwise very safe at supplement doses.
🏷️ Other Names
Cyanocobalamin (synthetic B12)