SAFE

Crospovidone

Cross-linked polyvinylpyrrolidone (Kollidon CL)
Possibly Safe V2 Verified Excipients & Additives
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PubMed Studies
4
About

Cross-linked PVP polymer used as a super-disintegrant in tablets and as an insoluble adsorbent for poisons. Unlike soluble PVP, crospovidone is not absorbed. Very safe pharmaceutical excipient.

How it works (mechanism of action)

Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Not absorbed — passes through GI tract intact. Generally very safe. No significant adverse effects at excipient doses.

🏷️ Other Names
Cross-linked polyvinylpyrrolidone (Kollidon CL)
Updated: 2026-04-11
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